Data for 8028 persons from the NHANES cohort (US National Health and Nutrition Examination Survey) were analysed for correlations between serum PBDE (nine PBDEs, tri- to deca-BDE) and metabolic indicators of oxidative stress (bilirubin, CGT). After controlling for covariables, all except one of the PBDEs (a penta congener) and total PBDE were associated to bilirubin. The authors note that this apparent correlation requires verification by a larger cohort study but that it corresponds to evidence from in vitro and in vivo animal studies.
“Association between brominated flame retardants exposure and markers of oxidative stress in US adults: An analysis based on the National Health and Nutrition Examination Survey 2007–2016”, L. Han, Q. Wang, Ecotoxicology and Environmental Safety 263 (2023) 115253 https://doi.org/10.1016/j.ecoenv.2023.115253