Lethality and teratogenicity were tested using the standard fish species, zebrafish, for up to 96 hours after fertilisation of eggs. No significant mortality was observed at the concentrations tested, but the brominated diphenyl ether cogeners BDE-47 and BDE-99 showed developmental effects at 48 hours at tested 14 – 16 mg/l for the BDEs. AlPi (aluminium diethylphosphinate) showed no developmental toxicity, inducing no morphological changes after 96 hours at the highest concentration tested (30 mg/l). The authors conclude that the PIN FR AlPi may be considered a suitable alternative.
“A comparison of developmental toxicity of brominated and halogen-free flame retardant on zebrafish”, F.R. Abe et al., Ecotoxicology and Environmental Safety 208 (2021) 111745 https://doi.org/10.1016/j.ecoenv.2020.111745